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Dr. Thomas Classen
Lehrbeauftragter für 'Chemie für (Zahn-)Mediziner'
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Research interest: Secondary Metabolism | Dirigent Proteins | Halogenating Enzymes | Alkaloids | Biocatalysis (in flow)

Homepage of the RG Secondary Metabolism Enzymology

Teaching Portfolio & Teaching Awards

ORCID | ↗ResearcherID |ResearchGate | ↗GoogleScholar

Aufgabenfelder

Team leader ‘Secondary Metabolism Enzymology’ & Group Leader ‘Enzymology

 

Lebenslauf

Academic Stages

2025-2026External lecturer Bioorganic Chemistry
RWTH Aachen University
since 2023External lecturer Technical Biocatalysis
Management Center Innsbruck (AUT)
since 2016Lecturer Chemistry for Physicians
Heinrich Heine University Düsseldorf
since 2015Junior group leader Secondary Metabolism Enzymology
Institute of Bio- and Geosciences: Biotechnology
Forschungszentrum Jülich
since 2014Group leader Enzymology
Institute of Bioorganic Chemistry, Heinrich Heine University
July 2013Doctoral defence
»Über Enzyme als facettenreiche Katalysatoren in der Organischen Chemie«

2009-2012

 

Doctoral studies
Scholarship of the NRW Research School BioStruct
2009Master thesis at the group of Prof. Dr. Pietruszka
Institute for Bioorganic Chemistry
»Pyruvate dependent Aldolases – Development of a Screening«
2007Master studies in biochemistry at the
Heinrich Heine University Düsseldorf
2007Bachelor thesis at the group of Prof. Dr Groth
Institute for Biochemical Plant Physiology
2004Bachelor studies in biochemistry at the
Heinrich Heine University Düsseldorf
2003Abitur

 

Publikationsverzeichnis

Publications

An overview on the publications with Thomas Classen as author can be found in these repositories.

ORCID | ↗ResearcherID |ResearchGate | ↗GoogleScholar

© IBOC 2025

Nina Stadler M.Sc.
Wissenschaftliche Mitarbeiterin
02461-61-1696
E-Mail senden
Gebäude: 15.13
Etage/Raum: 304


Aufgabenfelder

Isolation and semisynthetic modification of potato alkaloids and investigation of their biological activity 

Lebenslauf

Academic Stages

Since 2022

 

Doctoral studies
2021Master thesis at the group of Prof. Ducho
Institute of Medicinal and Pharmaceutical Chemistry (Saarland University)
» Muraymycin-Analoga mit potenzieller Aktivität gegen Pseudomonas aeruginosa «
2019-2021Master studies in chemistry at
Saarland University
2018

Bachelor thesis at the group of Dr. Schäfer
Institute of Inorganic Chemistry (Saarland University)

» Untersuchungen zur Reaktivität von Natrium-(tricarbonylcyclopentadienyl)wolfram gegenüber Halogeniden der Gruppe 14 und 15 «

2014-2018Bachelor studies in chemistry at
Saarland University
2013Abitur

Awards & Scholarships

2013GDCh-Abiturientenpreis
Publikationsverzeichnis

F. Genzel, A. Wiese-Klinkenberg, S. Schleker, M. Bueno da Silva, N. Stadler, T. Classen, F. M. W. Grundler, J. Pietruszka, B. Usadel, Poster: “ToxPot - Evaluation of the Potential of Utilization of Potato-side Streams for Extraction of Alkaloids” 8th BioSC Forum 2022, Düsseldorf, Germany.

M. Bueno da Silva, N. Stadler, S. Schleker, F. M. W. Grundler, J. Pietruszka, B. Usadel, A. Wiese-Klinkenberg, T. Classen, F. Genzel, Poster: “ToxPot – Evaluation of the potential of utilizing potato-side streams for extraction of alkaloids” 6th BioSC Symposium 2022, Bonn, Germany.

M. Bueno da Silva, N. Stadler, B. Thiele, S. Schleker, F. M. W. Grundler, J. Pietruszka, B. Usadel, A. Wiese-Klinkenberg, T. Classen, F. Genzel, Poster: “ToxPot – Potato side-streams and their potential in a circular bioeconomy” 9th BioSC Forum 2023, Jülich, Germany.

S. Bredenbruch, N. Stadler, J. Pietruszka, F. M. W. Grundler, T. Classen, S. S. Schleker, Poster: “NovoStimAct Plant Biostimulant Activity of Novel Bacterial Biosurfactants” 9th BioSC Forum 2023, Jülich, Germany.

N. Stadler, M. Bueno da Silva, B. Thiele, F. M. W. Grundler, B. Usadel, A. Wiese-Klinkenberg, S. Schleker, F. Genzel, T. Classen, J. Pietruszka, Poster: “Potato side streams for alkaloid extraction as part of a circular bioeconomy” ECCE & ECAB 2023, Berlin, Germany. 

M. Bueno da Silva, N. Stadler, A. Wiese-Klinkenberg, T. Classen, S. Schleker, F. M. W. Grundler, J. Pietruszka, B. Usadel, F. Genzel, Poster: “ToxPot – Evaluation of the extraction of potato glycoalkaloids from side streams and their activity against microorganisms” 10th BioSC Forum 2024, Jülich, Germany.

S. Bredenbruch, N. Stadler, J. Pietruszka, F. M. W. Grundler, T. Classen, S. Schleker, Poster: “NovoStimAct Novel Bacterial Biosurfactants and Plant Stimulation Activity” 10th BioSC Forum 2024 in Jülich, Germany.

N. Stadler, M. Bueno da Silva, F. M. W. Grundler, B. Usadel, A. Wiese-Klinkenberg, S. Schleker, F. Genzel, J. Pietruszka, T. Classen, Poster: “Beyond the Tuber: Crafting High-Value Molecules from Potato Residues” 6th International Conference on Natural Products Research (ICNPR) 2024, Krakow, Poland.

N. Stadler, J. Pietruszka, T. Classen, Poster: “Evaluation of the Ecological Impact of Solanidine Production by Comparing Natural Product Extraction and Total Synthesis” 6th International Congress on Natural Products Utilization (ICNPU) 2025, Bansko, Bulgaria. (Received a Poster Award)

N. Stadler, J. Pietruszka, T. Classen, Talk: “Potato Side Streams Utilization: Creation of New Valuable Compounds Within a Circular Bioeconomy Approach” 6th International Conference on Natural Products Utilization (ICNPU) 2025, Bansko, Bulgaria.

N. Stadler, J. Pietruszka, T. Classen, “Utilizing Potato Side Streams for the Creation of New Valuable Molecules and Circular Bioeconomy” 29th Annual Green Chemistry and Engineering Conference, Pittsburgh, USA.

 

 

 

 

 

 

 

 

 

 

Philipp Sowa M.Sc.


Aufgabenfelder

„Alkaloid semisynthesis“

 

Lebenslauf

Academic Stages

2022-today

 

Doctoral studies at the group of Prof. Dr. Jörg Pietruszka

Institute of Bioorganic Chemistry

(Heinrich-Heine-University Düsseldorf)

2021-2022

Scientist at the group of Prof. Dr. Dirk Tischler

Microbial Biotechnology

(Ruhr-University Bochum)
» Industrial Project: EnzymePrint«

2021

Master thesis at the group of Prof. Dr. Dirk Tischler

Microbial Biotechnology

(Ruhr-University Bochum)
» Enantioselective epoxidation by indole monooxygenases«

2019-2021Master studies in Biology at
Ruhr-University Bochum
2019

Bachelor thesis at the group of Prof. Dr. Dirk Tischler

Microbial Biotechnology

(Ruhr-University Bochum)

» A novel reductase of Gordonia rubripertincta CWB2 «

2016-2019Bachelor studies in Biology at
Ruhr-University Bochum
2016Abitur

Awards & Scholarships

2023Posterpreis für “Valuable compounds from lupin plant resource side stream” im Rahmen 7th international BioSC Symposium  6. - 7. November 2023
Vorträge
Poster Philipp Sowa, Sebastian Myllek, Mirai Alosh, Jan Lukas Heise, Dr. Thomas Classen, Dr. Marco Löhrer, Prof. Ulrich Schaffrath, Prof. Jörg Pietruszka “Valuable compounds from lupin plant resource side stream” im Rahmen 7th international BioSC Symposium  6. - 7. November 2023
Poster Philipp Sowa, Sebastian Myllek, Mirai Alosh, Ashley Beers, Jan Lukas Heise, Dr. Thomas Classen, Dr. Marco Löhrer, Prof. Ulrich Schaffrath, Prof. Jörg Pietruszka "Harnessing lupin defense mechanisms for enhanced quinolizidine alkaloid production" im Rahmen 8th international BioSC Symposium
Konsortiumsposter Dr. M. Löhrer, Prof. U. Schaffrath, Prof. Björn Usadel, Dr. Anika Wiese-Klinkenberg, Dr. Sebastian Beier, Mansi Singh, Prof. J. Pietruszka, Dr. T. Classen, Philipp Sowa, Prof. M. Hartmann, J. Klink-Lehmann, Bodo Rehm, "P³roLucas - Optimization of plant performance and products for lupin cascade use" präsentiert von Philipp Sowa im Rahmen 11th BioSC Forum und BioSC Begutachtung

 
Vortrag 15 min “Optimization of plant performance and products for lupin cascade use” gehalten von Marco Loehrer, Philipp Sowa im Rahmen 10th BioSC Forum 17. Mai 2024
Vortrag 20 min “From Lupins to High Value Alkaloids: A Bioeconomic-Journey” gehalten von Philipp Sowa im Rahmen 5th European Conference on Natural Products 22. - 24. Oktober 2024
Vortrag 15 min "Functional molecules for farming and pharma: Identification - characterization - synthesis – application" gehalten von Anika Wiese-Klinkenberg, Philipp Sowa im Rahmen 11th BioSC Forum 01. April 2025

Catharina Gronkowsky M.Sc.


ORCID-ID 0009-0008-3408-4982

 

Lebenslauf

Academic Stages

Since 2024Doctoral studies at the group of Prof. Dr. Jörg Pietruszka
Institute of Bioorganic Chemistry (Heinrich Heine University Düsseldorf)
2024

Master thesis at the group of Dr. Thomas Classen
Institute of Bioorganic Chemistry (Heinrich Heine University Düsseldorf)

»Studies on enzymatic tryptophan halogenation – a regioselective synthesis toolbox«

2022-2024Master studies in Biochemistry at
Heinrich Heine University Düsseldorf
2022

Bachelor thesis at the group of Prof. Dr. Karl-Erich Jaeger
Institute of Molecular Enzyme Technology (Heinrich Heine University Düsseldorf)

»Towards establishing a Pseudomonas putida-based mutasynthesis for the production of deoxyviolacein derivatives«

2019-2022Bachelor studies in Biochemistry at
Heinrich Heine University Düsseldorf
2019Abitur

Awards & Scholarships

2025

GBM-Masterpreis 

2021-2024

German Academic Scholarship Foundation 

2020-2021

Deutschlandstpiendium HHU 
Publikationsverzeichnis

Publications

M. Schatton, M. Haase, J. Tenhaef, C. Gronkowsky, S. Noack, J. Pietruszka, Chemoenzymatic Total Synthesis of Lansai B, 2025, DOI: 10.1002/chem.202500740

 

Posters & Presentations

C. Gronkowsky, T. Classen, J. Pietruszka, AUFBRUCH Winter School 2024 (Jülich DE), poster: ‘Etablierung einer Bibliothek aus Halogenasen zur regioselektiven Synthese von Tryptophan Derivaten‘

C. Gronkowsky, J. Pietruszka, T. Classen, DECHEMA Summer School Biotransformation 2025 (Bad Herrenalb, DE), poster: ‘Towards sustainable Halogenation: Investigation on Tryptophan Halogenases and Flavin Reductases’